• A.G. Mendoza-Madrigal Departamento de Ingeniería Bioquímica, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional
  • J.J. Chanona-Pérez Departamento de Ingeniería Bioquímica, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional
  • H. Hernández-Sánchez Departamento de Ingeniería Bioquímica, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional
  • E. Palacios-González Laboratorio de Microscopia de Ultra Alta Resolución, Instituto Mexicano del Petróleo
  • G. Calderón-Domínguez Departamento de Ingeniería Bioquímica, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional
  • J. V. Méndez-Méndez Centro de Nanociencias y Micro y Nanotecnologías, Instituto Politécnico Nacional
  • J. Blasco Centro de Agroingeniería. Instituto Valenciano de Investigaciones Agrarias, (IVIA)
  • L.A. Villa-Vargas Centro de Investigación en Computación, Instituto Politécnico Nacional
Keywords: biosensors, cantilever, atomic force microscopy, foods


A review of state the art about the structure, classification and operation of biosensors applied in food and biological areas is presented. This review is focused to mechanical biosensors that use mili, micro and nanocantilevers. Basic concepts of atomic force microscopy and optical systems, used as testing platform of biosensors are described. The most funcionalized strategies and geometrical configurations are also explained. Mathematical methods for evaluating the performance in static and dynamic mode of the mechanical biosensors are reviewed and examples of application in biological and food areas are provided. An overall description of the operational effect of operation conditions and design variables on the sensitivity devices is also proposed. A brief description of the design processes and manufacturing of cantilevers based silicon technology as well as information about BioMEMS and BioNEMS are provided. Finally, overall trends in research, development and commercialization of biosensors are described briefly as well as probable areas of development in food biosensors. Thereby, this review provides an overall view of biosensors, as an exploratory guide to identify the most important aspects of this technology.


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How to Cite
Mendoza-Madrigal, A., Chanona-Pérez, J., Hernández-Sánchez, H., Palacios-González, E., Calderón-Domínguez, G., Méndez-Méndez, J. V., Blasco, J., & Villa-Vargas, L. (2020). MECHANICAL BIOSENSORS IN BIOLOGICAL AND FOOD AREA:. Revista Mexicana De Ingeniería Química, 12(2), 205-225. Retrieved from
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