A review of comparison study between Corona Viruses (SARS-CoV, MERS-CoV) and Novel Corona Virus (Covid-19)
Currently (March 2020) COVID-19 disease has recorded the most significant number of deaths and cases as compared to coronaviruses’ types. Initially, the virus was referred to as 2019-nCoV. Subsequently, the International Committee on Taxonomy of Viruses (ICTV) named it the SARS-CoV-2 virus because it is significantly similar to the causative agent of (SARS-CoVs). All Nidovirales’s viruses are positive-sense non-segmented and enveloped viruses. They have big genomes for the RNA viruses. The critical differences in the families of Nidovirus are noted in the type, sizes, and the number of structural proteins. The variances cause substantial alterations in the morphology and structure of the virions and nucleocapsids. Currently, the COVID- 19 diseases have recorded the most significant number of deaths and cases as compared to other kinds of coronaviruses. In conclusion, since the outbreak of (COVID-19) disease in China, the illness is spreading very quickly across the globe. There was no evidence showing that the viruses were manufactured in laboratories or engineered till now. Extensive lab work on the mechanisms of infection and genetic factors such as polymorphism that may play an essential role in disease is needed urgently.
Ashour, H. M. (2020). Insights into the recent 2019 novel coronavirus (SARS-CoV).Retrieved.
Baig, A.M., Khaleeq, A., Ali, U. and Syeda, H. (2020). Evidence of the COVID-19 Virus Targeting the CNS: Tissue Distribution, Host–Virus Interaction, and Proposed Neurotropic Mechanisms. ACS Chemical Neuroscience.
Bao, L. et al. (2020). Preprint at BioRxiv
Begley, S. (2020). Who is getting sick, and how sick? A breakdown of coronavirus risk by
Benbacer, L., Kut, E., Besnardeau, L., Laude, H., &Delmas, B. (1997). Interspecies aminopeptidase-N chimeras reveal species-specific receptor recognition by canine coronavirus, feline infectious peritonitis virus, and transmissible gastroenteritis virus. Journal of virology, 71(1), 734-737.
Cai, J., Sun, W., Huang, J., Gamber, M., Wu, J., & He, G. (2020). Indirect virus transmission in cluster of COVID-19 cases, Wenzhou, China, 2020. Emerging Infectious Diseases, 26(6). https://doi.org/10.3201/eid2606.200412
Cao, Y., Li, L., Feng, Z., Wan, S., Huang, P., Sun, X., Wen, F., Huang, X., Ning, G., & Wang, W. (2020). Comparative genetic analysis of the novel coronavirus (2019-nCoV/SARS-Cov-2) receptor ACE2 in different populations. Cell Discovery, 6(1). https://doi.org/10.1038/s41421-020-0147-1
Cascella, M, Rajnik, M, Cuomo, A, Dulebohn, S.C., Di Napoli, R. (2020). Features, evaluation
cases caused by a novel coronavirus, Wuhan, China. Retrieved from:
Centre for Evidence-Based Medicine. (2020). Global COVID-19 case fatality rates. Retrieved
Clinical microbiology reviews, 26(1), 135–162. https://doi.org/10.1128/CMR.00077-12
Danser, A. J., Epstein, M., &Batlle, D. (2020). Renin-angiotensin system blockers and the COVID-19 Pandemic
Delmas, B., Gelfi, J., L'Haridon, R., Sjöström, H., & Laude, H. (1992).Aminopeptidase N is a major receptor for the enteropathogenic coronavirus TGEV. Nature, 357(6377), 417-420.
demographic factors. Retrieved from:www.statnews.com › 2020/03/03 › who-is-getting-sick-and-how-sick-
Dominguez, S. R., Travanty, E. A., Qian, Z., & Mason, R. J. (2013). Human coronavirus HKU1
Dongchi Zhao, Dan Xu, Qing Gong, Jing Liao, Huixia Yang, Wei Hou&Yuanzhen Zhang. (2020). Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records, Volume 395, Issue 10226, P809-815. Retrieved from:www.thelancet.com › lancet › article
European Centre for Disease Prevention and Control. (2020). Cluster of pneumonia
European Centre for Disease Prevention and Control. (2020). Factsheet for health professionals
Fang, L., Karakiulakis, G., & Roth, M. (2020).Antihypertensive drugs and risk of COVID-19? – Authors' reply. The Lancet Respiratory Medicine. https://doi.org/10.1016/s2213-2600(20)30159-4
Fang, L., Karakiulakis, G., & Roth, M. (2020b). Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection? The Lancet Respiratory Medicine. https://doi.org/10.1016/s2213-2600(20)30116-8
Fehr, A. R., & Perlman, S. (2015). Coronaviruses: an overview of their replication www.cebm.net › global-covid-19-case-fatality-rates
from: www.mdpi.com › pdf
Galveston (TX): University of Texas Medical Branch at Galveston; 1996. Chapter 60. Available from:
Genetic Engineering &Biotehnology News. (2020). ‘Coronavirus evolved naturally, and it is Giuseppina La Rosa; Marta Fratini; Simonetta Della Libera; Marcello Iaconelli& Michele
Hofmann, H., Pyrc, K., van der Hoek, L., Geier, M., Berkhout, B., &Pöhlmann, S. (2005). Human coronavirus NL63 employs the severe acute respiratory syndrome coronavirus receptor for cellular entry. Proceedings of the National Academy of Sciences, 102(22), 7988-7993.
Hossam, M. A, Walid F. E, Md. Masudur R & Hatem A. E. (2020).infection of primary human type II alveolar epithelial cells: cytopathic effects and innate immune response. PloS one, 8(7), e70129. https://doi.org/10.1371/journal.pone.0070129
International Health Regulations (2005) Emergency Committee regarding the outbreak of novel coronavirus (2019-nCoV). Retrieved from: www.who.int › Newsroom › Detail
Jacobs, S. E., Lamson, D. M., St George, K., & Walsh, T. J. (2013).Human rhinoviruses.
KHN Morning Briefing. (2020). Summaries of health policy coverage from major news
Kikkert, M. (2019).Innate immune evasion by human respiratory RNA viruses. Journal of Innate Immunity, 12(1), 4-20. https://doi.org/10.1159/000503030
Kuster, G. M., Pfister, O., Burkard, T., Zhou, Q., Twerenbold, R., Haaf, P., Widmer, A. F., &Osswald, S. (2020). SARS-cov2: Should inhibitors of the renin–angiotensin system be withdrawn in patients with COVID-19? European Heart Journal. https://doi.org/10.1093/eurheartj/ehaa235
Li, B. X., Ge, J. W., & Li, Y. J. (2007). Porcine aminopeptidase N is a functional receptor for the PEDV coronavirus. Virology, 365(1), 166-172.
Li, W., Moore, M. J., Vasilieva, N., Sui, J., Wong, S. K., Berne, M. A., ...&Choe, H. (2003). Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus. Nature, 426(6965), 450-454.
Li, X., Geng, M., Peng, Y., Meng, L., & Lu, S. (2020). Molecular immune pathogenesis and diagnosis of COVID-19. Journal of Pharmaceutical Analysis. https://doi.org/10.1016/j.jpha.2020.03.001
Miura, T. A. &Holmes. K. V. (2009). Host-pathogen interactions during coronavirus infection
Muscillo.(2013).Viral infections acquired indoors through airborne, droplet or contact transmission. Retrieved from: www.scielosp.org › article › aiss
Nedellec, P., Dveksler, G. S., Daniels, E., Turbide, C., Chow, B., Basile, A. A., ...&Beauchemin, N. (1994). Bgp2, a new member of the carcinoembryonic antigen-related gene family, encodes an alternative receptor for mouse hepatitis viruses. Journal of virology, 68(7), 4525-4537.
Neher, R, A, Dyrdak, R, Druelle, V, Hodcroft E, B, Albert, J. (2020). Potential impact of not a laboratory construct,’ genetic study shows. Retrieved from: www.genengnews.com › Virology › Coronavirus
of primary alveolar epithelial cells. Journal of leukocyte biology, 86(5), 1145–1151.https://doi.org/10.1189/jlb.0209078
Peng, X., Xu, X., Li, Y. et al.(2020). Transmission routes of 2019-nCoV and controls in dental
Peng, X., Xu, X., Li, Y., Cheng, L., Zhou, X., &Ren, B. (2020). Transmission routes of 2019-nCoV and controls in dental practice. International Journal of Oral Science, 12(1), 1-6. https://doi.org/10.1038/s41368-020-0075-9
Perico, L., Benigni, A., &Remuzzi, G. (2020). Should COVID-19 concern nephrologists? Why and to what extent? The emerging impasse of Angiotensin blockade. Nephron, 1-9. https://doi.org/10.1159/000507305
Raj, V. S., Mou, H., Smits, S. L., Dekkers, D. H., Müller, M. A., Dijkman, R., ... & Thiel, V. (2013). Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC. Nature, 495(7440), 251-254.
Randy, C&Winn, C. (2020).How doctors can potentially significantly reduce the number of deaths from Covid-19. Retrieved from: www.vox.com › coronavirus-covid-19-deaths-china-treatment-cytoki.
Retrieved from: www.clickorlando.com › news › 2020/03/19 › fda-is-fast-tracking-ma. Retrieved from: www.nicd.ac.za › risk-factors-of-the-coronavirus
Reuters. (2020). Is coronavirus a leaked biological weapon? Scientists don't think so. Retrieved from: www.livemint.com › news › world › is-coronavirus-a-leaked-biologic.SARS).
Schultze, B., &Herrler, G. (1992). Bovine coronavirus uses N-acetyl-9-O-acetylneuraminic acid as a receptor determinant to initiate the infection of cultured cells. Journal of General Virology, 73(4), 901-906.
Scripps Research Institute. (2020). COVID-19 coronavirus epidemic has a natural origin. Science Daily.Retrieved March 22, 2020 from www.sciencedaily.com/releases/2020/03/200317175442.htm.
Singhal, T. (2020).A Review of Coronavirus Disease-2019 (COVID-19).Indian J Pediatr87,
Smith, T. R. F. et al. (2020). Preprint at Research Square https://doi.org/10.21203/rs.3.rs-
Speck, E. (2020). FDA is fast tracking malaria drug to possibly treat coronavirus.
Tesini, B, L. (2020). Coronaviruses and acute respiratory syndromes (COVID-19, MERS, and
The Economic Times. (2020). Coronavirus a product of natural evolution, not lab made: Study
The National Institute for Communicable Diseases.(2019). Risk factors of the coronavirus.
The World Health Organisation (WHO). (2020). Coronavirus disease 2019 (COVID-19: Situation report-32. Retrievedfrom: www.who.int › docs › situation-reports › 20200221-sitrep-32-covid-19
The World Health Organisation (WHO). (2020).
Tignanelli, C. J., Ingraham, N. E., Sparks, M. A., Reilkoff, R., Bezdicek, T., Benson, B., Schacker, T., Chipman, J. G., &Puskarich, M. A. (2020).Antihypertensive drugs and risk of COVID-19? The Lancet Respiratory
Tresnan, D. B., Levis, R., & Holmes, K. V. (1996). Feline aminopeptidase N serves as a receptor for feline, canine, porcine, and human coronaviruses in serogroup I. Journal of virology, 70(12), 8669-8674.
TWC Product and Technology LLC. (2020). Coronavirus not man-made, has natural origin: Tyrrell DAJ, Myint SH. Coronaviruses. In: Baron S, editor. Medical microbiology.4th edition.
Weingartl, H., Czub, M., Czub, S., Neufeld, J., Marszal, P., Gren, J., ...&Grudeski, E. (2004). Immunization with modified vaccinia virus Ankara-based recombinant vaccine against severe acute respiratory syndrome is associated with enhanced hepatitis in ferrets. Journal of virology, 78(22), 12672-12676.
Wu X, Cai Y, Huang X, Yu X, Zhao L, Wang F, et al. (2020). Co-infection with SARS-CoV-
Wu, C., Chen, X., Cai, Y., Zhou, X., Xu, S., Huang, H., ...& Song, J. (2020). Risk factors associated with acute respiratory distress syndrome and death in patients with coronavirus disease 2019 pneumonia in Wuhan, China. JAMA internal medicine.
Yeager, C. L., Ashmun, R. A., Williams, R. K., Cardellichio, C. B., Shapiro, L. H., Look, A. T., & Holmes, K. V. (1992). Human aminopeptidase N is a receptor for human coronavirus 229E. Nature, 357(6377), 420-422.
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